![]() |
|
Viagra (Sildenafil)Viagra (Sildenafil Citrate), discovered by Pfizer, is available on the market since 1998 and has earned prominent public recognition. Sildenafil has the longest patient experience and the most extensive data confirming its efficacy for sexual dysfunction (impotence). Sildenafil increases the body's ability to achieve and maintain an erection during sexual stimulation. It is often prescribed for erection problems due to antidepressants or psychotropics. Interestingly, sildenafil seems to be a promising sexual enhancer for women. Researchers suggest, that it may enhance vasodilation in the clitoris and relaxation of vaginal smooth muscle, improving sexual function in women. Onset of action: 30-60 minutes. Viagra should be used with caution by people who have a heart disease or high blood pressure. Buy Original Pfizer Viagra
More Information
How to use?
Viagra dosage Doses range from 25 mg to 100 mg, depending on the needed effect. If you buy Viagra for the first time start with the initial dosage of 50 mg. If you are over 65, have liver or kidney problems, or are taking potent CYP3A4 inhibitors a dose of 25 mg may be sufficient. Viagra may be taken anywhere from 0.5 to 4 hours before sexual activity. Some men need to take sildenafil 3 or 4 times before it works. The maximum recommended dose is 100 mg. How Viagra works? Sildenafil is a Phosphodiesterase Enzyme Inhibitor. It works by increasing the blood flow to the penis, essential for successful love-making. Sildenafil enhances the effects of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5) in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 causes increased levels of cyclic guanosine monophosphate (cGMP) in the erectile tissue, resulting in smooth muscle relaxation and inflow of blood. Sildenafil is sold as Revatio for pulmonary arterial hypertension (PAH). |
Quick facts
|