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Brief Information
  • Generic name: Topiramate
  • Brand names: Topamax
  • Drug class: Anticonvulsant
  • Dosages: 25 mg, 50 mg, 100 mg tablets
  • Avalable as generic? No

Buying Information

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Detailed Information

Topiramate (brand name Topamax) an anticonvulsant. Topamax is used alone or in combination with other medications to prevent seizures in adults and children who are at least 2 years old.

Topiramate (Topamax) is also used to prevent migraine headaches. The drug will only prevent migraine headaches or reduce the number of attacks. It will not treat a headache that has already begun.

How to take

  • Topamax can be taken with or without food. Avoid breaking the tablets; the medication has a bitter taste.
  • Topamax increases your risk of developing kidney stones. To prevent this problem, be sure to take Topamax with plenty of fluids.
  • Do not abruptly stop taking Topamax. If the drug isn't withdrawn gradually, the frequency of your seizures could increase.
  • Topamax has been known to cause a potentially serious condition known as metabolic acidosis (an increase of acid in the blood). Contact your doctor immediately if you experience symptoms of metabolic acidosis such as rapid breathing, an irregular heartbeat, confusion, lethargy, fatigue, or loss of appetite.
  • Seek emergency medical attention if you have a sudden change in vision and pain around or behind the eyes. Topamax has been known to trigger severe nearsightedness along with increased pressure inside the eye. The problem usually occurs within 1 month of starting treatment.

Topamax dosage

ADULTS

Seizures
Topamax therapy usually begins with a dose of 50 mg once daily during the first week. The daily dosage is then increased each week until, by the eighth week, the patient is taking 200 mg twice a day. If you are also taking Dilantin or Tegretol, the dosage of Topamax may need adjustment.

Prevention of Migraine Headaches:
The recommended total daily dose is 100 mg a day, taken in two divided doses. Your doctor will increase the dose slowly over 4 weeks.
The usual regimen is as follows: Week 1: No morning dose; take 25 mg at night. Week 2: Take 25 mg in the morning and again at night. Week 3: Take 25 mg in the morning and 50 mg at night. Week 4: Take 50 mg in the morning and again at night.

CHILDREN

The usual daily dose for children 2 to 16 years of age is 5 to 9 mg for every 2.2 pounds of body weight, divided into two doses. Topamax therapy usually begins with a dose of 25 mg (or less) once daily during the first week. The daily dosage is then increased each week until the doctor is satisfied with the patient's response. It may take eight weeks to reach the ideal dose.

DOSAGE ADJUSTMENT

For people with poor kidney function, the dosage is usually cut in half. On the other hand, those undergoing hemodialysis may need a supplemental dose. Likewise, the doctor may adjust your dosage if you have liver problems.

Interesting facts

non prescription Topamax
  • Topamax is a sulfamate-substituted monosaccharide, related to fructose, a rather unusual chemical structure for an anticonvulsant.
  • It is recommended to maintain adequate fluid intake to reduce chance of developing kidney stones.
  • Topamax was originally designed as an oral hypoglycaemic agent afterward approved as anticonvulsant.