OriginalDrugs

Tamiflu (Oseltamivir)

  • Active ingredient: Oseltamivir phosphate
  • Drug class: Antiviral, Neuraminidase Inhibitors
  • Company name: Hoffmann La Roche Inc

Tamiflu (Oseltamivir phosphate) is an antiviral medicine effective against influenza types A and B. When started during the first 2 days of the illness, Oseltamivir speeds recovery and reduces the duration of flu by 1.5 days.

It is also used for the prevention of influenza. Tamiflu can prevent the flu as long as you continue taking the prescription.

How effective is Tamiflu?

According to a major review of over 50 studies published in 2006, Tamiflu is effective against the flu in about 60% of cases.

Oseltamivir phosphate is active against both influenza types A and B. The drug can reduce the severity and duration of illness or help to reduce the chance of getting the flu. The sooner Tamiflu is started after flu symptoms onset, the more effectively drug works.

As the flu virus penetrates into the body, it forms new copies of itself and spreads from cell to cell. Tamiflu fights the virus by preventing the release of new copies from infected cells. Oseltamivir works by blocking a key viral enzyme, neuraminidase, which is involved with viral replication.

Tamiflu may not prevent the development of immunity - when used as prophylaxis, oseltamivir can prevent illness while permitting sub-clinical infection and development of protective antibody against circulating influenza viruses.

What are the disadvantages and side effects?

  • About 10 - 15% of persons experience nausea and vomiting.
  • There is no such thing as generic Tamiflu. Being available exclusively as brand medication made by Hoffman La Roche it is pretty expensive.
  • Limited production capacity. The manufacturing process for oseltamivir is complex and time-consuming, involving a complex, 10-step process that takes approximately 6-8 months.
  • To be effective as much as possible for flu prevention, the drug must be taken each day during the influenza outbreak, not just the peak period. This makes use of Tamiflu as prophylaxis questionable and potentially very expensive.
  • Timing is very critical when used for flu treatment. The drug should be started within 2 days of the start of symptoms to be effective. When you need the prescription for Tamiflu and the speed of getting the medication is important you can order online with Next Day delivery.
  • Benefits may be limited when used as treatment - oseltamivir can reduce the duration of uncomplicated influenza by approximately one day. The drug's effectiveness in preventing serious influenza complications is unclear.

Buying Roche Tamiflu

Dosage Quantity Pharmacy Price Shipping Buy
75 mg 10 tablets MPLLC.net $189 $18

According to the FDA, Tamiflu may be used to treat the Swine flu (2009 H1N1 flu virus).

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Dosage Information

Take Tamiflu without regard to food. If stomach upset occurs, take with food to reduce stomach irritation.

To clear up your infection completely, take Tamiflu for the full course of treatment. Keep taking the prescription even if you feel better in a few days.

Treatment of Influenza: The usual dosage is 75 mg taken twice daily (morning and evening) for 5 days. If you have kidney disease, take a 75 mg dose once a day.

Prevention of Influenza: The usual dosage is 75 mg taken once a day for at least 7 days. If there is a flu epidemic, your doctor may recommend that you continue taking Tamiflu for up to 6 weeks. If you have kidney disease, take a 75 mg capsule every other day, or 30 mg of liquid once a day.

For children 1 to 12 year old the dose is determined by a pediatrician according to the child's weight. Tamiflu should not be used to treat the flu in children under 1 year old.

Quick facts

Tamiflu
  • One advantage of Tamiflu over Relenza is availability of oseltamivir suspension formulation.
  • Important advantage of Oseltamivir (Tamiflu) over old antivirals amantadine and rimantadine is the lack of neurologic side effects such as dizziness, insomnia, depression, anxiety, and irritability.
  • The most common side effects of oseltamivir (Tamiflu) are nausea and vomiting, which are usually subsideed when the medication is taken with food.