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Prednisone (Prednisolone)

Prednisone and Prednisolone are prescription steroid drugs used to reduce inflammation and alleviate symptoms in a variety of disorders.

Prednisolone is a potent anti-inflammatory, anti-allergic and anti-rheumatic medication with rapid onset of action. It can be a life saver for many people.

Prednisone vs Prednisolone: What is the difference?

While prednisone and prednisolone have the same indications, are equally effective, and are considered to be equivalent, they should not be confused. Prednisone is an inactive drug precursor and must be converted by the liver into prednisolone. For this reason, prednisolone is a preferred prescription choice for people with liver diseases.

Prednisone is used to treat:

  • Endocrine disorders: primary or secondary adrenocortical insufficiency, congenital adrenal hyperplasia, nonsuppurative thyroiditis
  • Rheumatic disorders: as adjunctive therapy for short-term administration in: psoriatic arthritis rheumatoid arthritis, including juvenile rheumatoid arthritis, ankylosing spondylitis, acute and subacute bursitis, acute nonspecific tenosynovitis, acute gouty arthritis, post-traumatic osteoarthritis, synovitis of osteoarthritis, epicondylitis
  • Collagen diseases: systemic lupus erythematosus, systemic dermatomyositis (polymyositis), acute rheumatic carditis
  • Dermatologic diseases: pemphigus, bullous dermatitis herpetiformis, severe erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, mycosis fungoides, severe psoriasis, severe seborrheic dermatitis
  • Allergy: seasonal or perennial allergic rhinitis, serum sickness, bronchial asthma, contact dermatitis, atopic dermatitis, drug hypersensitivity reactions
  • Respiratory diseases: bronchial asthma, symptomatic sarcoidosis, Loeffler's syndrome not manageable by other means, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy, aspiration pneumonitis

Buy Prednisolone Online

Note: Prednisone is a synthetic corticosteroid converted to Prednisolone in the liver. We list prices for Prednisolone available for buying online.

Dosage Quantity Pharmacy Price Buy
20 mg 30 tablets 4RX.com $25
20 mg 90 tablets 4RX.com $66
20 mg 150 tablets 4RX.com $105
40 mg 30 tablets 4RX.com $35
40 mg 60 tablets 4RX.com $66
40 mg 90 tablets 4RX.com $98
5 mg 30 tablets Easy.md $26.24
5 mg 60 tablets Easy.md $30.32
5 mg 90 tablets Easy.md $34.41
10 mg 30 tablets Easy.md $27.41
10 mg 60 tablets Easy.md $35.59
10 mg 90 tablets Easy.md $43.75
20 mg 30 tablets Easy.md $29.46
20 mg 60 tablets Easy.md $39.66
20 mg 90 tablets Easy.md $49.88
40 mg 30 tablets Easy.md $27.99
40 mg 60 tablets Easy.md $43.74
40 mg 90 tablets Easy.md $60.37


Drug Information

Prednisone risks and side effects

  • adrenal suppression
  • weight gain (redistribution of body fat to places that are undesirable, particularly the face, back of the neck, and abdomen)
  • risk of steroid-induced diabetes
  • high blood pressure
  • increased susceptibility to infections
  • can cause peptic ulceration
  • increased calcium excretion (bone thinning)
  • prolonged use may produce posterior, subcapsular cataracts or glaucoma
  • hirsutism (excessive growth of body hair)
  • thin skin and easy bruising

How to take

  • You should take Prednisone (prednisolone) with food to avoid stomach upset.
  • Take the medication exactly as prescribed by your doctor. Dosages are kept to an absolute minimum.
  • If you have been taking prednisone for a period of time, you will probably need an increased dosage before, during, and after any stressful situation. Always consult your doctor if you are expecting stress and think you may need a temporary dosage increase.
  • When stopping prednisone, tapering off is better than quitting abruptly. Generally, it is not recommended to stop corticosteroid prescription without doctor's advice.
  • Corticosteroids can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had.
  • Do not get a smallpox vaccination or any other immunization while you are taking prednisone.
  • Diseases such as chickenpox or measles can be very serious or even fatal in both children and adults who are taking the steroid. Try to avoid exposure to these diseases.

Prednisone (prednisolone) dosage

Dosage is determined by the condition being treated and your response. Typical starting doses can range from 5 mg to 60 mg a day. Once you respond to the drug, the dose can be gradually lowered to the minimum effective amount. For treatment of acute attacks of multiple sclerosis, doses of as much as 200 mg per day may be given for a week, followed by 80 mg every other day for a month.

It is very convenient to obtain Prednisone without the excess fee to get a prescription. However, international pharmacy does not provide prescription instructions regarding the proper dosage.

Quick facts

Prednisone
  • Prednisolone influences the biochemical behaviour of most tissues of the body.
  • When prednisone is compared with the naturally occurring glucocorticoids, cortisone and cortisol (hydrocortisone), its anti-inflammatory effects are 5 times more potent whilst its mineralocorticoid properties are less pronounced.