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Imitrex (Sumatriptan) Prescription

Imitrex (sumatriptan succinate) is an antimigraine medication, known as triptan. It is used to treat migraine headaches with or without aura (flashing lights, wavy lines, dark spots) and is effective when used at any time during the attack. Also, it may be prescribed for acute treatment of cluster headaches.

Very effective migraine treatment...
Imitrex provides rapid relief from migraine headache with the onset of relief within 30 minutes of a 100 mg oral dose. The drug may decrease migraine symptoms such as nausea, photophobia, phonophobia. Sumatriptan is suitable as long-term prescription treatment.

...But not suitable for everyone
A major concern with Sumatriptan is its potential to cause cardiovascular side effects. Triptans are contraindicated for people with known cardiovascular or cerebrovascular disease. People with cardiovascular risk factors, but without established disease, should use Imitrex (Sumatriptan) with caution under the doctor's supervision.

Sumatriptan (Generic Imitrex)

Although Imitrex patent protection has expired in 2009, the generic Sumatriptan is not yet widely available in US. Therefore we provide prices for generic Imitrex available at overseas pharmacy, where you can buy the medication without having a prescription.

Dosage Quantity Pharmacy Price Buy
100 mg 5 tablets 4RX.com $39
100 mg 10 tablets 4RX.com $69
100 mg 20 tablets 4RX.com $135
100 mg 40 tablets 4RX.com $259
100 mg 80 tablets 4RX.com $499


Imitrex (US)

US customers have an option to request the brand Imitrex and receive the prescription provided by U.S. physician, that will include the dosage recommendations, instructions on how to take, and precautions information.

Dosage Quantity Pharmacy Price Shipping Buy
25 mg 9 tablets MPLLC.net $229 $18
25 mg 27 tablets MPLLC.net $575 $18
50 mg 9 tablets MPLLC.net $209 $18
50 mg 27 tablets MPLLC.net $519 $18
100 mg 9 tablets MPLLC.net $215 $18
100 mg 27 tablets MPLLC.net $525 $18

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Drug Information

How does it work?

Imitrex works by narrowing blood vessels in the brain, which helps to relieve migraines.

Sumatriptan is a serotonin 5-HT 1 receptor agonist ("triptan"). It is structurally similar to serotonin, which is one of the receptors that serotonin binds to. The specific receptor subtype it activates is present in the cranial and basilar arteries. Activation of these receptors causes vasoconstriction of those dilated arteries. Sumatriptan is also shown to decrease the activity of the trigeminal nerve.

How to take

  • It is best to take a dose of Sumatriptan as soon as you notice symptoms of a migraine attack.
  • If your migraine symptoms go away and then come back, or if you have a partial response to the first dose, you may take a second dose as prescribed by your doctor. Wait at least 2 hours between doses.
  • If your symptoms do not improve after the first dose, do not take a second dose for the same attack. Contact your doctor.
  • Overuse of Sumatriptan can cause your headache to become worse. Do not take the higher dose or use more often than prescribed.
  • The drug should not be used to prevent or reduce the number of migraine headaches you have.
  • Imitrex has potential for drug interactions. Avoid concurrent use with antidepressants, ergotamine, sibutramine.

Prescription dosage

Follow recommendations on the prescription label or ask your doctor if you have questions about the medication use. Do not change the dosage regimen for Imitrex without doctor's approval.

The usual adult dose is one 25, 50, or 100 mg tablet taken with water or other liquid. The most you should take at one time is 100 mg, and the most you should take in 1 day is 200 mg. Doses should be spaced at least 2 hours apart. If you have liver disease, you should not take more than 50 mg at one time.

Interesting facts

imitrex
  • Sumatriptan is the first of a class of medications known as the "triptans". It is a specific medication for aborting migraine headaches. It is also effective in cluster headache as an abortive medication.
  • Imitrex was specifically designed just for migraines and was the first medicine of its kind to target the nerves and blood vessels believed to trigger the migraine.