OriginalDrugs

Lexapro (Escitalopram)

Escitalopram oxalate (Lexapro, Cipralex) is an SSRI antidepressant. It is a selective serotonin reuptake inhibitor, and is used to treat depression, anxiety disorders, and panic disorder.

If you are going to buy Lexapro, you may want to know more about it and to talk with your psychiatrist if this particular antidepressant is right for you.

  • Lexapro is the most selective of all the Selective Serotonin Reuptake Inhibitors (SSRIs). It is suitable as a first-line treatment for moderate to severe depression. Lexapro is often more effective than citalopram (Celexa) and other SSRIs in the treatment of depression, including severe depression1.
  • Generally, it is fast-acting antidepressant with a more rapid onset of effect than other SSRIs2. Improvement in symptoms occurs within one to two weeks after beginning it.
  • Sexual side effects with Lexapro are generally less frequent than with fluoxetine, paroxetine, or sertraline. It is generally weight neutral.
  • Withdrawing from Lexapro results in fewer and less intense discontinuation symptoms than from either paroxetine or venlafaxine.
  • Escitalopram has relatively low potential for interactions.

Buying Generic Lexapro (International)

Unfortunately, generic Lexapro is not available in the USA yet. However, customers from other countries have a chance to buy cheap Escitalopram from the international pharmacy at a reasonable price.

Manufacturer: Cipla

Description Quantity Price Buy
Escitalopram 10 mg 30 tablets $35
Escitalopram 10 mg 60 tablets $59
Escitalopram 10 mg 90 tablets $79
Escitalopram 10 mg 180 tablets $139
Escitalopram 20 mg 30 tablets $59
Escitalopram 20 mg 60 tablets $89
Escitalopram 20 mg 90 tablets $119
Escitalopram 20 mg 180 tablets $195

More Information

How does Lexapro work?

Escitalopram binds to the serotonin transport molecule and boosts the concentration of serotonin in the synapse. A wonderful feature of escitalopram is that it is the most selective of all the SSRIs, having little or negligible affinity for numerous other receptors.

How long Lexapro takes to start working?

Many people on Lexapro begin to feel better within 1 or 2 weeks, although the full effect may take 4 to 6 weeks. It tends to work faster than other SSRIs. For most people, it may take as long as 3-4 weeks to experience the optimal effects.

The duration of treatment depends on the personal psychiatric history. It will be longer for those who have had two or more previous episodes of depression. Once your depression is gone you may continue Lexapro for up to 6-12 months. A small percentage of people will still have residual depressive symptoms after their antidepressant is stopped.

Dosage

The recommended dose is 10 mg once a day. If necessary, the dose can be increased to 20 mg after a minimum of 1 week. For seniors and people with liver impairment it is prudent to start with 5 mg per day and not go beyond 10 mg per day.

If your depression symptoms don't improve after 4-6 weeks of Lexapro your psychiatrist may switch you to another antidepressant.

How to come off Lexapro

Don't discontinue Lexapro abruptly. Abrupt cessation may result in withdrawal symptoms such as confusion, lethargy, insomnia, tingling or shock like sensations. Onset of these symptoms usually occurs within a week of discontinuation or dose reduction and may last from a few days to 3 weeks.

Reducing in 10-25% steps every 2 weeks would be a sensible attempt to come off. More gradual steps allow more time for the brain to adapt to the decreasing levels of escitalopram. Keep in mind that Lexapro is available in liquid form which allows you to reduce at a very gradual pace.


References
  • 1. Kennedy SH, Andersen HF, Lam RW. Efficacy of escitalopram in the treatment of major depressive disorder compared with conventional selective serotonin reuptake inhibitors and venlafaxine XR: a meta-analysis. J Psychiatry Neurosci. 2006 Mar;31(2):122-31. PubMed
  • 2. Kasper S, Spadone C, Verpillat P, Angst J. Onset of action of escitalopram compared with other antidepressants: results of a pooled analysis. Int Clin Psychopharmacol. 2006 Mar;21(2):105-10. PubMed
Quick facts
Lexapro

escitalopram
  • Escitalopram oxalate was released two years before the patent for Celexa was due to expire.
  • It is a cleaner, improved version of citalopram, namely the S-isomer molecule.
  • About 47% of patients who don't respond to Celexa benefit from Lexapro.