Effexor XR (Venlafaxine) Prescription

• Generic name: Venlafaxine hydrochloride (HCL)
• Brand name: Effexor XR (Extended Release)
• Drug class: Serotonin and norepinephrine reuptake inhibitors (SNRIs)

Effexor (Venlafaxine) is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It is used to treat depression, anxiety disorders, and panic disorder.

Occasionally, doctors use Effexor or Venlafaxine as an "off-label" prescription for treating migraine headaches, fibromyalgia, chronic pain, attention-deficit hyperactivity disorder (ADHD), or hot flashes.

Venlafaxine hydrochloride comes in two formulations: immediate-release tablets (Effexor) and extended-release capsules (Effexor XR). Extended-release form offers the convenience of once-daily dosing and may be better tolerated.

It has quick onset of antidepressant effect and may work faster than other medications. Relative order of speed of onset from quickest to slowest is Effexor, Lexapro, Wellbutrin & Celexa, Cymbalta, Paxil & Prozac, and Zoloft.

The most frequent side effect is nausea. According to the studies, about 50% of people experience nausea during the first 8 weeks of venlafaxine. Other common undesirable effects are dry mouth, insomnia, somnolence, dizziness, and abnormal ejaculation.

Venlafaxine (Generic Effexor XR)

Dosage	Quantity	Pharmacy	Price	Buy
75 mg	60 capsules	4RX.com	$23
75 mg	90 capsules	4RX.com	$33
75 mg	180 capsules	4RX.com	$65
75 mg	360 capsules	4RX.com	$126
150 mg	60 capsules	4RX.com	$51
150 mg	90 capsules	4RX.com	$69
150 mg	180 capsules	4RX.com	$136
150 mg	360 capsules	4RX.com	$270

Generic Effexor ER (US)

When you buy Effexor XR via Health Solutions Network, the medication is shipped from within the US with FedEx overnight. Also, you will be provided with doctor's prescription instruction on how to use the medication.

Dosage	Quantity	Pharmacy	Price	Shipping	Buy
37.5 mg	30 capsules	MPLLC.net	$175	$18
37.5 mg	90 capsules	MPLLC.net	$393	$18
75 mg	30 capsules	MPLLC.net	$184	$18
75 mg	90 capsules	MPLLC.net	$435	$18
150 mg	30 capsules	MPLLC.net	$195	$18
150 mg	90 capsules	MPLLC.net	$469	$18

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Unlike the selective-serotonin reuptake inhibitors (SSRIs), Effexor (venlafaxine) has a dual mechanism of action. It works by altering the neurotransmission of both serotonin and norepinephrine, two important neurotransmitters in the brain.

The reuptake effects of venlafaxine are dose dependent. At low doses (<150 mg/day), the drug acts like the SSRIs. At intermediate to high doses, the additional effects on noradrenaline reuptake become more substantial.

How to take

• It may take several weeks before you begin to feel better. Your doctor should check your progress periodically.
• Take Effexor XR once at the same time each day. Swallow the capsule whole with water. Do not divide, crush, or chew it. However, if you have trouble swallowing pills, you may take the drug by carefully opening the capsule and sprinkling the entire contents on a spoonful of applesauce, followed by a glass of water.
• Your doctor will prescribe Effexor with caution if you have high blood pressure, heart, liver, or kidney disease or a history of seizures or mania (extreme agitation or excitability).
• The significant drug interactions may occur when venlafaxine is combined with MAOIs, cimetidine, SSRIs, tricyclics, and haloperidol.

Effexor dosage

When you receive the prescription for Effexor XR (or for Venlafaxine) follow the instuctions even if your dosage is different.

The usual starting dose is 75 mg a day, divided into 2 or 3 smaller doses, and taken with food. If needed, your doctor may gradually increase daily dose in steps of no more than 75 mg at a time up to a maximum of 375 mg per day. If you have kidney or liver disease or are taking other medications, the doctor will adjust your dosage accordingly.

Effexor XR dosage

For both depression and anxiety, the usual starting dose is 75 mg once daily taken with food, although some people begin with a dose of 37.5 mg for the first 4 to 7 days. Your doctor may gradually increase the dose, in steps of no more than 75 mg, up to a maximum of 225 mg daily. If you have kidney or liver disease you need dose adjustments.

Effexor Withdrawal

Effexor is known for high rate of withdrawal symptoms. Taking the drug in the evening if it is usually taken in the morning or forgetting to take the daily dose just once may induce sudden and severe physical and mental disturbances.

Venlafaxine requires very gradual tapering before completely stopping the medication. Therefore, don't change the dosage schedule or stop using Effexor without discussing it with doctor.

A number of clinical reports of severe Effexor withdrawal symptoms have been published. Widely consulted drug information services, such as Medscape DrugInfo, American Hospital Formulary Service Drug Information, and First DataBank, list the following withdrawal symptoms as "serious": agitation, anorexia, anxiety, confusion, impaired coordination, diarrhea, dizziness, dry mouth, dysphoric mood, fasciculation, fatigue, headaches, hypomania, insomnia, nausea, nervousness, nightmares, sensory disturbances (including shock-like electrical sensations), somnolence, sweating, tremor, vertigo, and vomiting.

If you are looking for antidepressant without a prescription, you should have clear indications for its use and be aware about potential side effects.

Also, keep in mind that if your symptoms don't improve with Effexor you may need a different prescription antidepressant.