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Celexa (Citalopram) Without a Prescription
Citalopram hydrobromide (Celexa) is an antidepressant with extremely high selectivity for serotonin (5-HT) reuptake inhibition. Although officially citalopram is indicated only for the treatment of depression, it is also used to treat anxiety, panic, obsessive-compulsive disorder, and posttraumatic stress disorder. Celexa is notable for its low incidence of drug interactions compared to other SSRIs. So it is suitable for elderly people and those with coexisting disorder. Withdrawal symptoms after its discontinuation are relatively mild.
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How does Celexa work? Citalopram works by preventing the re-uptake of one neurotransmitter serotonin (5-HT). This results in increased serotonin levels in the brain. Serotonin is known to elevate mood. Citalopram consists of what is called a racemic mixture, an equal mix of S (+) and R (-) enantiomers, the molecules that are mirror images of each other. As it turns out, much of the antidepressant activity of citalopram is due to the S molecule. Caution: Citalopram also has affinity for histamine H1 receptors, which contributes to mild antihistamine and sedating qualities. As a result, some people suffer from extreme tiredness, lethargy, apathy, and emotional lability. How to take:
Celexa dosage: The usual starting dose of is 20 mg once a day, taken either in the morning or evening. Dosage is usually titrated up slowly to 40 mg once daily after at least a week has passed. However, the dose usually is not more than 60 mg a day. While every person is different, you may notice improvement in your depression with Citalopram in 1 to 4 weeks. The duration of treatment may vary, but is usually at least 6 months. For older adults and those who have liver problems it is recommended to start at 20 mg once a day. |
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