Spironolactone (Aldactone)

• Generic name: Spironolactone
• Brand names: Aldactone, Novo-Spiroton, Spiractin, Spirotone, Verospiron, Berlactone
• Drug class: Potassium-sparing Diuretics

Spironolactone (Aldactone) is a prescription diuretic with anti-androgenic properties. It flushes excess salt and water from the body and controls high blood pressure. It is used in the diagnosis and treatment of hyperaldosteronism, a condition in which the adrenal gland secretes too much aldosterone (a hormone that regulates the body's salt and potassium levels).

Spironolactone is also used in treating other conditions that require the elimination of excess fluid from the body. These conditions include congestive heart failure, high blood pressure, cirrhosis of the liver, kidney disease, and unusually low potassium levels in the blood. When used for high blood pressure, Aldactone can be taken alone or with other high blood pressure medications.

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Dosage	Quantity	Pharmacy	Price	Shipping	Buy
25 mg	30 tablets	Easy.md	$26.24	Free
25 mg	60 tablets	Easy.md	$32.37	Free
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100 mg	60 tablets	Easy.md	$78	Free
100 mg	90 tablets	Easy.md	$106	Free

Spironolactone for Acne

Spironolactone (Aldactone) is a steroidal anti-androgen that lowers levels of the hormone androgen, which stimulates the skin’s oil glands. It is effective, safe, and inexpensive treatment for acne caused by hormonal fluctuations. This off-label use of spironolactone is principally indicated for women. This drug can cause gynecomastia in men.

Typical doses for acne treatment range from 25 to 200 mg daily.

According to results of a long-term study1, the long-term treatment of acne with spironolactone in women is safe.

The most common side effects are diuretic effect, menstrual irregularities, breast tenderness, fatigue, and headache. Some women are treated for several years without side effects.

How to take

• Spironolactone (Aldactone) may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
• Spironolactone can raise your body's potassium levels. This is more likely to occur in people with kidney problems, diabetes, in the elderly, or if the patient is severely ill. Potassium levels must be closely monitored in people with any of these problems or illnesses. If not treated, high potassium levels can be fatal.
• Avoid becoming overheated or dehydrated during exercise and in hot weather.
• Do not use this medication if you have kidney disease, urination problems, or high levels of potassium in your blood. Do not use potassium supplements or other prescription and non-prescription diuretics while you are taking spironolactone.

Spironolactone dosage

Primary Hyperaldosteronism:
Initial dosages are used to determine the presence of primary hyperaldosteronism (too much secretion of the adrenal hormone aldosterone). People can be tested with Spironolactone over either a long or a short period of time.

In the long test, you take 400 mg per day for 3 to 4 weeks. If your potassium levels and blood pressure are corrected with this dosage in this time period, your physician may assume you have this condition.

In the short test, you receive 400 mg per day for 4 days. A laboratory test compares potassium levels while you are on the drug and after the it is stopped. Your doctor may then make a diagnosis.

After the diagnosis of primary hyperaldosteronism is made and confirmed by more tests, the usual dose is 100 to 400 mg per day, prior to surgery. In those who are not good candidates for surgery, Spironolactone is given over the long term at the lowest effective dose.

Fluid Retention (Congestive Heart Failure, Cirrhosis of the Liver, or Kidney Disorders):
The usual starting dosage is 100 mg daily either in a single dose or divided into smaller doses. However, your doctor may have you take daily doses as low as 25 milligrams or as high as 200 mg. Your doctor may choose to adjust your dosage after an initial 5-day trial period or add another diuretic medication to this one.

Essential Hypertension (High Blood Pressure):
The usual starting dosage is 50 to 100 mg daily in a single dose or divided into smaller doses. This medication may be given with another diuretic or with other high blood pressure medications. It may be up to 2 weeks before the full effect of Aldactone is seen. Your doctor can then adjust the dosage according to your response.

Hypokalemia (Potassium Loss):
Your doctor may have you take daily dosages of 25 mg to 100 mg when potassium loss caused by the effects of a diuretic cannot be treated by a potassium supplement.

International customers can purchase Spironolactone without doctor's prescription by choosing the offer from provided price table.

References

• 1. Shaw JC, White LE. Long-term safety of spironolactone in acne: results of an 8-year followup study. J Cutan Med Surg. 2002 Nov-Dec;6(6):541-5.